An ability of poorly differentiated cells of different genesis, including tumor stem-like cells (TSCs),
to internalize extracellular double-stranded DNA (dsDNA) fragments was revealed in …

… molecule with a positively charged molecule(s) on the surface of a stem-like tumor cell; 2)
binding of the dsDNA probe to a tumor stem cell surface protein(s) via the formation of a strong …

Group-specific component macrophage-activating factor (GcMAF) is the vitamin D 3 -binding
protein (DBP) deglycosylated at Thr 420 . The protein is believed to exhibit a wide range of …

Background/Aim: Oncolytic adenoviruses are promising therapeutic agents against both the
bulk of tumor cells and cancer stem cells. The present study intended to test the oncolytic …

The main problem related to the studies focusing on group-specific component protein-derived
macrophage-activating factor (GcMAF) is the lack of clarity about changes occurring in …

… drastic depletion of cells from both S and G2/M phases and … with the simultaneous growth
of the S phase fraction (21% vs. 8… of massive exit of cells into the S phase, as the most suitable …

It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective
and radiotherapeutic effects. The experiments conducted in this study directly demonstrated …

The purpose of the article Protection from ionizing radiation is the most important component
in the curing malignant neoplasms, servicing atomic reactors, and resolving the situations …

Background/Aim: We compared the therapeutic efficacy of two recently developed experimental
anticancer technologies: 1) in situ vaccination based on local immunotherapy with CpG …

Krebs-2 solid carcinoma was cured using a new “3+ 1” strategy for eradication of Krebs-2
tumor-initiating stem cells. This strategy was based on synchronization of these cells in a …