Glioblastoma (GBM) is a primary neuroepithelial tumor of the central nervous system,
characterized by an extremely aggressive clinical phenotype. Patients with GBM have a poor …

Purpose: HER2 overexpression has been associated with a poor prognosis and resistance
to therapy in breast cancer patients. We are developing molecular probes for in vivo …

[18F]FBEM-ZHER2:342-Affibody molecule—a new molecular tracer for in vivo monitoring of
HER2 expression by positron emission tomography | European Journal of Nuclear Medicine …

Thermosensitive liposomes are attractive vehicles for the delivery and release of drugs to
tumors. To improvethe targeting efficacy for breast cancer treatment, an 8.3-kDa HER2-specific …

Background Near infrared (NIR) photoimmunotherapy (PIT) is a new type of cancer treatment
based on a monoclonal antibody (mAb)-NIR phthalocyanine dye, (IR700) conjugate. In …

Trastuzumab prolongs survival in HER2 positive breast cancer patients. However,
resistance remains a challenge. We have previously shown that ADAM17 plays a key role in …

Morgan, NY, Kramer-Marek, G., Smith, PD, Camphausen, K. and Capala, J. Nanoscintillator
Conjugates as Photodynamic Therapy-Based Radiosensitizers: Calculation of Required …

Multispectral near-infrared I/shortwave infrared fluorescence imaging is a versatile system
enabling high tumor-to-background signal for safer and more complete resection of pediatric …

The role of HER4 in breast cancer is controversial and its role in relation to trastuzumab
resistance remains unclear. We showed that trastuzumab treatment and its acquired resistance …

Nuclear medicine is a multidisciplinary field that develops and uses instrumentation and
tracers (radiopharmaceuticals) to study physiological processes and noninvasively diagnose, …