The objective of this study was to examine the effect of autophagy on stress-induced M2
macrophage polarization in the tumor microenvironment of breast cancer and to determine …

Objective To examine the effect of pSer9-GSK-3β on breast cancer and to determine
whether the underlying metabolic and immunological mechanism is associated with ROS/eIF2B …

Inhibitors targeting Bruton's tyrosine kinase (BTK) have revolutionized the treatment for various
B-cell malignancies but are limited by acquired resistance after prolonged treatment as a …

Background Indoleamine-2,3-dioxygenase 1 (IDO1) is an important enzyme for altering the
tumour microenvironment and assisting tumour cells to escape the immune system. Results …

Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role
in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is …

In this study, we investigate the effect of miR-34a expression and biological characteristics
of breast cancer stem cells (BCSCs). The mammospheres were formed from murine breast …

miR‐21a is well‐known to inhibit PTEN expression. We have previously shown that PTEN
suppressed the transformation of M2 macrophages in the tumor microenvironment. Therefore, …

Objective To investigate the inducing effects of chemokines [fractalkine (FKN), IP-10] and
different signal pathway inhibitors on NK cells in the tumor microenvironment (TME). Methods …

The fatigue stress amplitude of the welded cross plate-hollow sphere joint (WCPHSJ) in a
grid structure varies due to the random loading produced by suspending cranes. A total of 14 …

High-strength bolts play a crucial role in securing prefabricated steel structures and are
extensively employed in offshore wind turbines and grid structures [1-3]. Despite their resilience, …