Exercise has been shown to improve postischemia perfusion of normal tissues; we investigated
whether these effects extend to solid tumors. Estrogen receptor–negative (ER-, 4T1) and …

Dual emissive properties of solid-state difluoroboron β-diketonate-poly(lactic acid) (BF 2 bdk-PLA)
materials have been utilized as biological oxygen sensors. Dyes with red-shifted …

Hypoxia-inducible factor 1 (HIF-1) is a master transcription factor that controls cellular
homeostasis. Although its activation benefits normal tissue, HIF-1 activation in tumors is a major …

The human growth factor receptor type 2 (HER2) is overexpressed in breast as well as other
types of cancer. Immuno-PET, a noninvasive imaging procedure that could assess HER2 …

Zipper-interacting protein kinase (ZIPK) regulates Ca 2+ -independent phosphorylation of
both smooth muscle (to regulate contraction) and non-muscle myosin (to regulate non-…

The Cdc25 phosphatase promotes entry into mitosis through the removal of inhibitory
phosphorylations on the Cdc2 subunit of the Cdc2/CyclinB complex. During interphase, or after …

Cranial irradiation is a standard therapy for primary and metastatic brain tumors. A major
drawback of radiotherapy (RT), however, is long-term cognitive loss that affects quality of life. …

DAPK1 and ZIPK (also called DAPK3) are closely related serine/threonine protein kinases
that regulate programmed cell death and phosphorylation of non-muscle and smooth muscle …

Surface modification of nanoparticles and biosensors is a dynamic, expanding area of research
for targeted delivery in vivo. For more efficient delivery, surfaces are PEGylated to impart …

Pregnancy coordinately alters the contractile properties of both vascular and uterine smooth
muscles reducing systemic blood pressure and maintaining uterine relaxation. The precise …