[HTML][HTML] Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis

X Ding, Z Zheng, G Zhao, L Wang, H Wang… - Microbial Cell …, 2022 - Springer
Background Menaquinone-7 (MK-7), which is associated with complex and tightly regulated
pathways and redox imbalances, is produced at low titres in Bacillus subtilis. Synthetic …

[HTML][HTML] Engineering microbial consortia of Elizabethkingia meningoseptica and Escherichia coli strains for the biosynthesis of vitamin K2

…, Z Zheng, G Zhao, L Wang, H Wang, XM Ding… - Microbial Cell …, 2022 - Springer
Background The study and application of microbial consortia are topics of interest in the
fields of metabolic engineering and synthetic biology. In this study, we report the design and …

[HTML][HTML] Preparation of Cellulose-Based Flocculant and Its Application in the Enrichment of Vitamin K2 in Fermentation Supernatant

…, Z Zheng, H Wang, L Wang, G Zhao, H Tang, X Ding… - Polymers, 2022 - mdpi.com
Nutritional food supplements and pharmaceutical products produced with vitamin K 2 as
raw materials a very promising market in the global scope. The main production method of …

[HTML][HTML] Adaptive laboratory evolution for improved tolerance of vitamin K in Bacillus subtilis

X Ding, Z Zheng, G Zhao, L Wang, H Wang… - Applied Microbiology and …, 2024 - Springer
Menaquinone-7 (MK-7), a subtype of vitamin K 2 (VK 2 ), assumes crucial roles in coagulation
function, calcium homeostasis, and respiratory chain transmission. The production of MK-…

Effect of solution supersaturation on crystal formation of Vitamin K2 based on near infrared spectroscopy analysis technology

…, H Wang, L Wang, G Zhao, H Tang, X Ding… - Journal of Crystal …, 2023 - Elsevier
Polymorphism is frequently encountered in most small molecule drugs and vitamin supplements,
and the physical and chemical parameters of crystalline drugs may directly affect the …

Analysis of the progression of intraductal proliferative lesions in the breast by PCR-based clonal assay

Q Yu, Y Niu, Y Yu, XM Ding, YR Shi - Breast cancer research and …, 2009 - Springer
Purpose To analyze the progression in patients with a morphological diagnosis of
intraductal proliferative lesions by PCR-based clonal assay. Materials and methods An X-…

[HTML][HTML] Three cases of karyomegalic interstitial nephritis with novel FAN1 mutations from a Chinese family

H Zhu, Y Liu, X Ding, X Liu, L Xu… - Nefrología (English …, 2023 - revistanefrologia.com
Karyomegalic interstitial nephritis (KIN) is an exceedingly rare disease characterized with
enlarged tubular nucleus and presented with a slowly progressive renal failure, leading to end-…

Significance of β-tubulin expression in breast premalignant lesions and carcinomas

Y Gao, Y Niu, X Ding, Y Yu - Chinese Journal of Clinical Oncology, 2008 - Springer
Objective To explore the expression of β-tubulin in premalignant lesions and carcinomas of
the breast, and to observe the relationship of its expression with breast cancer pathological …

Preliminary study on the expression and the significance of S-phase kinase associated protein 2 in atypical ductal hyperplasia and breast cancer

Y Lü, Y Niu, X Ding, X Xiao, Y Yu - Chinese Journal of Clinical Oncology, 2006 - Springer
… Yan LO Yun Niu Xiumin Ding Xuqi Xiao Yong Yu … 5 Zheng XY, Ding W, Xie LP, et al. The
study on relationship of Skp2 and p27kip1 expression with clinical and pathological feature of …

The significance of minimally invasive core needle biopsy and immunohistochemistry analysis in 235 cases with breast lesions

Y Niu, T Liu, X Cao, X Ding, L Wei, Y Gao… - Chinese Journal of Clinical …, 2009 - Springer
Objective To evaluate core needle biopsy (CNB) as a minimally invasive method to examine
breast lesions and discuss the clinical significance of subsequent immunohistochemistry (…