We studied the self-reported information needs of 47 physicians during a half day of typical
office practice. The physicians raised 269 questions about patient management. Questions …

For successful use of radiolabeled monoclonal antibodies (MAbs) for diagnosis and therapy,
it is helpful to understand both global and microscopic aspects of antibody biodistribution. …

The solution structure of the ectodomain of simian immunodeficiency virus (SIV) gp41 (e‐gp41),
consisting of residues 27–149, has been determined by multidimensional heteronuclear …

The pharmacokinetics of an immunoglobulin G1 (IgG1) and its F(ab′) 2 and Fab′ fragments
following iv administration in mice has been studied by constructing a physiologically …

In order to understand the pharmacology of monoclonal antibodies and their conjugates,
one must consider both global and microscopic aspects of antibody distribution. Here we …

The solution structure of cyanovirin-N, a potent 11,000 M r HIV-inactivating protein that binds
with high affinity and specificity to the HIV surface envelope protein gp120, has been solved …

Clustering analysis of tumor cell cytotoxicity profiles for the National Cancer Institute (NCI)'s
open compound repository has been used to catalog over 1100 metal or metalloid …

In order to study the inferences of structure for mechanism, the collective motions of the
retroviral reverse transcriptase HIV-1 RT (RT) are examined using the Gaussian network model (…

Microtubules (MT), along with a variety of associated motor proteins, are involved in a range
of cellular functions including vesicle movement, chromosome segregation, and cell motility. …

Recently, we developed a simple analytical model based on local residue packing densities
and the distribution of tertiary contacts for describing the conformational fluctuations of …