The Inveon dedicated PET (DPET) scanner is the latest generation of preclinical PET systems
devoted to high-resolution and high-sensitivity murine model imaging. In this study, we …

The intrinsic nature of small-molecule chemotherapeutics, including i) limited aqueous
solubility, ii) systemic toxicity due to non-specific whole-body distribution, and iii) potential …

Alu repeated sequences arising in DNA of the human lineage during about the last 30 million
years are closely similar to a modern consensus. Alu repeats arising at earlier times share …

Laboratory mice routinely are housed at 20 to 22 C—well below the murine thermoneutral
zone of 29 to 34 C. Chronic cold stress requires greater energy expenditure to maintain core …

In six vervet monkeys, presynaptic striatal dopamine function was assessed longitudinally
by [ 18 F]fluoro-l-DOPA (FDOPA)–positron emission tomography (PET) after administration (2×…

Individual ventilated cages (IVC) are increasing in popularity. Although mice avoid IVC in
preference testing, they show no aversion when provided additional nesting material or the …

11 C-Acetate is currently being investigated as a new tracer for imaging neoplasms, most
notably prostate cancer and its metastases. Previously reported dose estimates for 11 C-…

A pretargeted oncologic positron emission tomography (PET) imaging that leverages the
power of supramolecular nanoparticles with in vivo bioorthogonal chemistry was demonstrated …

Many research institutions have a full suite of preclinical tomographic scanners to answer
biomedical questions in vivo. Routine multi-modality imaging requires robust registration of …

The combination of small-animal PET/CT scans and conventional imaging methods may
enhance the evaluation of in vivo biologic interactions of murine models in the study of prostate …