Answer questions and earn CME/CNE Pancreatic cancer is currently one of the deadliest of
the solid malignancies. However, surgery to resect neoplasms of the pancreas is safer and …

Background In a phase 1–2 trial of albumin-bound paclitaxel (nab-paclitaxel) plus gemcitabine,
substantial clinical activity was noted in patients with advanced pancreatic cancer. We …

The past decade of cancer research has been marked by a growing appreciation of the role
of immunity in cancer. Mutations in the tumour genome can cause tumours to express …

PURPOSE: Allogeneic granulocyte-macrophage colony-stimulating factor (GM-CSF)–secreting
tumor vaccines can cure established tumors in the mouse, but their efficacy against …

Purpose: Listeria monocytogenes (Lm)-based vaccines stimulate both innate and adaptive
immunity. ANZ-100 is a live-attenuated Lm strain (Lm ΔactA/ΔinlB). Uptake by phagocytes in …

Purpose To provide evidence-based recommendations to oncologists and others for the
treatment of patients with metastatic pancreatic cancer. Methods American Society of Clinical …

I n the United States there are 28,000 to 30,300 newly diagnosed cases of pancreatic cancer
and approximately an equal number of deaths per year from pancreatic cancer. 1, 2 Ductal …

The development of noninvasive methods to detect and monitor tumors continues to be a
major challenge in oncology. We used digital polymerase chain reaction–based technologies …

Purpose The trial objectives were to identify the maximum-tolerated dose (MTD) of first-line
gemcitabine plus nab-paclitaxel in metastatic pancreatic adenocarcinoma and to provide …

Purpose Contrary to the extensive data accumulated regarding pancreatic carcinogenesis,
the clinical and molecular features characteristic of advanced stage (stage III and IV) disease …