Soft-tissue sarcomas in adults

MA Clark, C Fisher, I Judson… - New England journal of …, 2005 - Mass Medical Soc
Soft-tissue sarcomas have traditionally been managed by wide excisional surgery and
radiotherapy, with chemotherapy reserved for advanced disease. However, advances in …

Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature

AL Folpe, T Mentzel, HA Lehr, C Fisher… - The American journal …, 2005 - journals.lww.com
PEComas, occasionally associated with the tuberous sclerosis complex, are defined by the
presence of perivascular epithelioid cells that coexpress muscle and melanocytic markers. …

Multiple newly identified loci associated with prostate cancer susceptibility

…, A Thompson, T Christmas, C Ogden, C Fisher… - Nature …, 2008 - nature.com
Prostate cancer is the most common cancer affecting males in developed countries. It shows
consistent evidence of familial aggregation, but the causes of this aggregation are mostly …

Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase …

…, S Marreaud, S Litière, C Hermans, C Fisher… - The lancet …, 2014 - thelancet.com
Background Effective targeted treatment is unavailable for most sarcomas and doxorubicin
and ifosfamide—which have been used to treat soft-tissue sarcoma for more than 30 years—…

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma

N Dupin, C Fisher, P Kellam, S Ariad… - Proceedings of the …, 1999 - National Acad Sciences
Human herpesvirus 8 (HHV-8, also called KSHV) is linked to the etiopathogenesis of Kaposi’s
sarcoma (KS), multicentric Castleman’s disease (MCD), and primary effusion lymphoma (…

Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells

…, TF Schulz, MM Kennedy, AK Graham, C Fisher… - Nature medicine, 1995 - nature.com
Kaposi's sarcoma (KS), a vascular tumour that contains characteristic spindle cells forming
slit-like spaces, may have an infectious aetiology. Recently, sequences of a new human …

Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread

…, O Al-Muderis, J Meirion Thomas, IR Judson, C Fisher… - Radiology, 2003 - pubs.rsna.org
PURPOSE: To investigate and describe the anatomic distribution, imaging features, and
pattern of metastatic spread of malignant gastrointestinal stromal tumors (GISTs). MATERIALS …

Impact of SYT-SSX Fusion Type on the Clinical Behavior of Synovial Sarcoma: A Multi-Institutional Retrospective Study of 243 Patients

…, JR Goldblum, SZ Ali, J Shipley, CS Cooper, C Fisher… - Cancer research, 2002 - AACR
Synovial sarcomas are aggressive spindle cell sarcomas containing in some cases areas of
epithelial differentiation. They consistently show a specific t(X;18;p11;q11), which usually …

Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel‐associated box in human synovial sarcoma.

AJ Crew, J Clark, C Fisher, S Gill, R Grimer… - The EMBO …, 1995 - embopress.org
We demonstrate that the cytogenetically defined translocation t(X;18)(p11.2;q11.2) found in
human synovial sarcoma results in the fusion of the chromosome 18 SYT gene to either of …

Angiomyofibroblastoma of the vulva: a benign neoplasm distinct from aggressive angiomyxoma

CDM Fletcher, WYW Tsang, C Fisher… - The American journal …, 1992 - journals.lww.com
Aggressive angiomyxoma of pelvic soft parts is a rare lesion with a high risk of recurrence.
We report 10 cases of angiomyofibroblastoma, a hitherto uncharacterized benign tumor of the …