PTEN regulates angiogenesis and VEGF expression through phosphatase-dependent and-independent mechanisms in HepG2 cells

T Tian, KJ Nan, SH Wang, X Liang, CX Lu… - …, 2010 - academic.oup.com
Hepatocellular carcinoma (HCC) is a typical hypervascular tumor, and increased levels of
vascular endothelial growth factor (VEGF) are associated with progression of HCC. Tumor …

[HTML][HTML] Clinical significance of HOTAIR expression in colon cancer

…, D Zhao, XQ Li, YX Cui, N Ma, CX Lu… - World journal of …, 2016 - ncbi.nlm.nih.gov
AIM: To detect the expression of the long noncoding RNA HOTAIR in colon cancer and
analyze its relationship with clinicopathological parameters of colon cancer. METHODS: Total …

Agents from amphibians with anticancer properties

CX Lu, KJ Nan, Y Lei - Anti-cancer drugs, 2008 - journals.lww.com
Amphibians have been found to be a source of agents with anticancer properties. Bufalin,
for example, is an anticancer agent that may induce apoptosis by its interaction with other …

PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway

…, ZP Ruan, SH Wang, X Liang, CX Lu - Oncology …, 2010 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Most patients
with HCC die within one year after diagnosis largely because of frequent tumor recurrence …

Quercetin enhances the effects of 5‑fluorouracil‑mediated growth inhibition and apoptosis of esophageal cancer cells by inhibiting NF‑κB

L ChuangXin, W Wen‑Yu, CUI Yao… - Oncology …, 2012 - spandidos-publications.com
Despite its limited success, 5‑fluorouracil (5‑FU) remains the primary chemotherapy agent for
the treatment of esophageal cancer. Quercetin has been demonstrated to inhibit the growth …

Delisheng, a Chinese medicinal compound, exerts anti-proliferative and pro-apoptotic effects on HepG2 cells through extrinsic and intrinsic pathways

C Lu, K Nan, Y Nie, Y Hai, M Jiao - Molecular biology reports, 2010 - Springer
The anti-proliferative, cytotoxic and apoptogenic activities of delisheng, a Chinese medicinal
compound, has been investigated. In this study, the hepatocarcinoma cell line (HepG2) and …

Anticancer peptide from Chinese toad (Bufo Bufo Gargarizans) skin enhanced sensitivity to 5-Fu in hepatocarcinoma cells (HepG2)

C Lu, W Wang, N Ma, Y Cui, X Li, Y Zhou - Clinical Oncology and Cancer …, 2011 - Springer
Objective To investigate the antiproliferative and apoptogenic activities of peptide extracted
from the Chinese toad (Bufo bufo gargarizans) skin (TSP) and its effects on hepatocarcinoma …

[HTML][HTML] Variants in the 3'-untranslated region of CUL3 is associated with risk of esophageal squamous cell carcinoma

JL Hu, XL Hu, CX Lu, XJ Chen, L Fu, Q Han… - Journal of …, 2018 - ncbi.nlm.nih.gov
Background: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers
in China. Recently, a study identified that cullin 3 (CUL3) was significantly mutated and …

Quantitative analysis on influence of secondary flow for centrifugal impeller internal flow

ZL Li, G Han, CX Zhou, HZ Cheng, XG Lu - Physics of Fluids, 2023 - pubs.aip.org
A comprehensive quantitative analysis of a high-loading transonic centrifugal compressor is
performed under the design point. The reason for secondary flow within the impeller is …

WITHDRAWN: Treatment of combining antiangiogenic therapy and cytotoxic chemotherapy reduce the cancer stem-like cell fraction in hepatocarcinoma xenografts

SY Yi, KJ Nan, F Wang, CX Lu, Y Kong, X Liang - 2008 - Elsevier
Recently, the cancer stem cell hypothesis has gained significant recognition as the descriptor
of tumorigenesis, but it is not known if hepatic cancer stem-like cells (CSLC) also rely on …