User profiles for Chen Zhang

Chen-Yu Zhang

- Verified email at nju.edu.cn - Cited by 58319

chen zhang

- Verified email at ivdc.chinacdc.cn - Cited by 14141

Chen Zhang

- Verified email at sjtu.edu.cn - Cited by 4330

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

…, J Gurr, AMC Rodríguez, A Lamsa, C Zhang… - Nature …, 2016 - nature.com
The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

Optimizing FPGA-based accelerator design for deep convolutional neural networks

C Zhang, P Li, G Sun, Y Guan, B Xiao… - Proceedings of the 2015 …, 2015 - dl.acm.org
Convolutional neural network (CNN) has been widely employed for image recognition
because it can achieve high accuracy by emulating behavior of optic nerves in living creatures. …

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

…, G Wu, W Tan, X Lu, C Fan, Q Wang, Y Liu, C Zhang… - Science, 2020 - science.org
Neutralizing antibodies could potentially be used as antivirals against the coronavirus disease
2019 (COVID-19) pandemic. Here, we report isolation of four human-origin monoclonal …

[HTML][HTML] Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

…, Y Zhang, J Chen, X Guo, Q Li, X Li, W Wang, Y Zhang… - Cell research, 2008 - nature.com
Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with
a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in …

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

…, JY Han, Y Chang, Y Liu, C Zhang, L Chen… - Nature …, 2018 - nature.com
Nanoscale robots have potential as intelligent drug delivery systems that respond to
molecular triggers 1 , 2 , 3 , 4 . Using DNA origami we constructed an autonomous DNA robot …

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity

…, CP Ye, R Coppari, PJ Enriori, B Choi, CY Zhang… - Nature, 2007 - nature.com
A subset of neurons in the brain, known as ‘glucose-excited’ neurons, depolarize and
increase their firing rate in response to increases in extracellular glucose. Similar to insulin …

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

J Lin, H Wu, PT Tarr, CY Zhang, Z Wu, O Boss… - Nature, 2002 - nature.com
The biochemical basis for the regulation of fibre-type determination in skeletal muscle is not
well understood. In addition to the expression of particular myofibrillar proteins, type I (slow-…

[HTML][HTML] Perinatal depressive and anxiety symptoms of pregnant women during the coronavirus disease 2019 outbreak in China

…, X Yang, D Zhang, J Zhang, X Wu, W Chen… - American journal of …, 2020 - Elsevier
Background On January 20, 2020, a new coronavirus epidemic with human-to-human
transmission was officially declared by the Chinese government, which caused significant public …

Capture and Catalytic Conversion of Polysulfides by In Situ Built TiO2‐MXene Heterostructures for Lithium–Sulfur Batteries

L Jiao, C Zhang, C Geng, S Wu, H Li… - Advanced Energy …, 2019 - Wiley Online Library
The detrimental shuttle effect in lithium–sulfur batteries mainly results from the mobility of
soluble polysulfide intermediates and their sluggish conversion kinetics. Herein, presented is a …

[PDF][PDF] Secreted monocytic miR-150 enhances targeted endothelial cell migration

…, J Yang, P Liu, T Xu, Q Yan, J Zhang, K Zen, CY Zhang - Molecular cell, 2010 - cell.com
MicroRNAs (miRNAs) are a class of noncoding RNAs that regulate target gene expression
at the posttranscriptional level. Here, we report that secreted miRNAs can serve as signaling …