Here we analyse genetic variation, population structure and diversity among 3,010 diverse
Asian cultivated rice (Oryza sativa L.) genomes from the 3,000 Rice Genomes Project. Our …

Both genetic variations and diet-disrupted gut microbiota can predispose animals to metabolic
syndromes (MS). This study assessed the relative contributions of host genetics and diet …

The human reference genome is still incomplete, especially for those population-specific or
individual-specific regions, which may have important functions. Here, we developed a …

The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a
common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. …

Background Third-generation sequencing platforms, such as PacBio sequencing, have been
developed rapidly in recent years. PacBio sequencing generates much longer reads than …

Oral microbiota plays a vital role in maintaining the homeostasis of oral cavity. Dental caries
are among the most common oral diseases in children and pathogenic bacteria contribute to …

The hypoxic environment imposes severe selective pressure on species living at high
altitude. To understand the genetic bases of adaptation to high altitude in dogs, we performed …

Background Estimating the number of genes in human genome has been long an important
problem in computational biology. With the new conception of considering human as a super…

Investigation of transcription factors (TFs) and their downstream regulated genes (targets) is
a significant issue in post-genome era, which can provide a brand new vision for some vital …

A pan-genome is the union of the gene sets of all the individuals of a clade or a species and
it provides a new dimension of genome complexity with the presence/absence variations (…