[HTML][HTML] Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo
Flavopiridol (L86-8275, HMR1275) is a cyclin-dependent kinase (Cdk) inhibitor in clinical
trials as a cancer therapy that has been recently shown to block human immunodeficiency …
trials as a cancer therapy that has been recently shown to block human immunodeficiency …
[HTML][HTML] Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
SH Chao, K Fujinaga, JE Marion, R Taube… - Journal of Biological …, 2000 - ASBMB
Flavopiridol (L86-8275, HMR1275) is a cyclin-dependent kinase (Cdk) inhibitor that is in
clinical trials as a cancer treatment because of its antiproliferative properties. We found that the …
clinical trials as a cancer treatment because of its antiproliferative properties. We found that the …
Academic self‐concept, learning motivation, and test anxiety of the underestimated student
D Urhahne, SH Chao, ML Florineth… - British Journal of …, 2011 - Wiley Online Library
Background. Teachers' judgments of student performance on a standardized achievement
test often result in an overestimation of students' abilities. In the majority of cases, a larger …
test often result in an overestimation of students' abilities. In the majority of cases, a larger …
Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription
The C-terminal domain (CTD) of the large subunit of RNA polymerase II plays a role in
transcription and RNA processing. Yeast ESS1, a peptidyl-prolyl cis/trans isomerase, is involved …
transcription and RNA processing. Yeast ESS1, a peptidyl-prolyl cis/trans isomerase, is involved …
Androgenetic haploid embryonic stem cells produce live transgenic mice
Haploids and double haploids are important resources for studying recessive traits and have
large impacts on crop breeding 1 , but natural haploids are rare in animals. Mammalian …
large impacts on crop breeding 1 , but natural haploids are rare in animals. Mammalian …
Forward scattering due to slow-down of the intermediate in the H + HD → D + H2 reaction
SA Harich, D Dai, CC Wang, X Yang, SD Chao… - Nature, 2002 - nature.com
Quantum dynamical processes near the energy barrier that separates reactants from products
influence the detailed mechanism by which elementary chemical reactions occur. In fact, …
influence the detailed mechanism by which elementary chemical reactions occur. In fact, …
Identification of p53 regulators by genome-wide functional analysis
The p53 tumor-suppressor protein is a critical mediator of cellular growth arrest and the
induction of apoptosis. To identify proteins involved in the modulation of p53 transcriptional …
induction of apoptosis. To identify proteins involved in the modulation of p53 transcriptional …
[HTML][HTML] New perspective on impact of folic acid supplementation during pregnancy on neurodevelopment/autism in the offspring children–a systematic review
Y Gao, C Sheng, R Xie, W Sun, E Asztalos… - PloS one, 2016 - journals.plos.org
It has been conclusively established that folic acid supplementation prior to and during early
pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We …
pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). We …
[HTML][HTML] Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors
Multipotent neural stem/progenitor cells hold great promise for cell therapy. The reprogramming
of fibroblasts to induced pluripotent stem cells as well as mature neurons suggests a …
of fibroblasts to induced pluripotent stem cells as well as mature neurons suggests a …
Effects of overexpression of X‐box binding protein 1 on recombinant protein production in Chinese hamster ovary and NS0 myeloma cells
X‐box binding protein 1 (XBP‐1) is a key regulator of the cellular secretory pathway and
unfolded protein response (UPR). It has been shown that the spliced form of XBP‐1, XBP‐1S, …
unfolded protein response (UPR). It has been shown that the spliced form of XBP‐1, XBP‐1S, …
