MicroRNAs (miRNAs) have been extensively studied over the decades and have been
proposed as potential molecular targets for cancer treatment. Studies have shown that miR-378 …

Objective: Anoikis is apoptosis that is induced when cells detach from the extracellular matrix
and neighboring cells. As anoikis serves as a regulatory barrier, cancer cells often acquire …

Objectives Dysregulation in miRNA expression contributes towards the initiation and
progression of metastasis by regulating multiple target genes. In this study, variations in miRNA …

The synthesis of the chiral core structure of the lissoclimide class of anti-tumour agents
containing three rings, including a chiral succinimide subunit and an exocyclic double bond, has …

Geranylated 4-phenylcoumarins DMDP-1 and DMDP-2 isolated from Mesua elegans were
elucidated for their role in inducing caspase-independent programmed cell death (CI-PCD) in …

Objectives Dysregulation in miRNA expression contributes towards the initiation and
progression of metastasis by regulating multiple target genes. In this study, variations in miRNA …

Lung cancer is the most commonly diagnosed cancer worldwide and ranks third in Malaysia
with increasing mortality rate over the years. This is often due to late presentation of disease …

Wastewater treatment remains a critical issue globally till date despite various technological
advancements and breakthroughs. Heavy metal in wastewater poses a great threat to …

Background Pembrolizumab (PD-1 inhibitor) and cetuximab (EGFR inhibitor) are active as
single agents and in combination with cytotoxic chemotherapy for recurrent or metastatic …

… To underline the anti-inflammatory effect of LA in the lung tissue via Nfr2/HO-1 signaling,
we analyzed the levels of Nrf2, inflammatory factors including NF-kB, IkB and COX-2 in lung …