The ATP-binding cassette transporters (ABC transporters) have been intensely studied over
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, …

Acquired resistance during cancer treatment is unfortunately a frequent event. There are
several reasons for this, including the ability of the ATP-binding cassette transporters (ABC …

Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia
has been shown to reprogram cells towards a stem cell phenotype associated with self-…

Brain tumors are considered one of the deadliest types of cancer, being challenging to treat,
especially due to the blood-brain barrier, which has been linked to treatment resistance. The …

The liquid biopsy era has brought several possibilities to improve precision in patient care.
Among the different sources of analytes, the cfDNA has been explored as a possible disease …

Acquired resistance during cancer treatment is unfortunately a frequent event. There are
several reasons for this, including the ability of the ATP-binding cassette transporters (ABC …

… Hemingway had the interpreter ask the policeman for an explanation, and the … Hemingway
would tell the story to his three sons years later. In the late 1940s, when Ernest Hemingway …

MicroRNAs (miRNAs) are small non-coding RNA molecules that play key regulatory roles in
cancer acting as both oncogenes and tumor suppressors. Due to their potential roles in …

… Monte-Carlo numerical simulations are conducted to establish trends of REACTs over … to
the pilots by controllers, and for the pilot to confirm the instructions. This process may contain …

The association between angiotensin-converting enzyme (ACE) genotypes and functional
decline in older adults remains controversial. To assess if ACE gene variations influences …