Glioblastoma cell–derived lncRNA-containing exosomes induce microglia to produce complement C5, promoting chemotherapy resistance
Z Li, X Meng, P Wu, C Zha, B Han, L Li, N Sun… - Cancer Immunology …, 2021 - AACR
… Caijun Zha; Caijun Zha … Ziwei Li, Xiangqi Meng, Pengfei Wu, Caijun Zha, Bo Han, Lulu Li,
Nan Sun, Tengfei Qi, Jie Qin, Yangong Zhang, Kaifu Tian, Shupeng Li, Changxiao Yang, Lejia …
Nan Sun, Tengfei Qi, Jie Qin, Yangong Zhang, Kaifu Tian, Shupeng Li, Changxiao Yang, Lejia …
[HTML][HTML] Neutrophil extracellular traps mediate the crosstalk between glioma progression and the tumor microenvironment via the HMGB1/RAGE/IL-8 axis
C Zha, X Meng, L Li, S Mi, D Qian, Z Li… - Cancer Biology & …, 2020 - ncbi.nlm.nih.gov
Objective: Neutrophil extracellular traps (NETs) produced by tumor-infiltrating neutrophils (TINs)
are associated with poor prognosis in patients with several types of cancer. However, …
are associated with poor prognosis in patients with several types of cancer. However, …
[HTML][HTML] Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways
X Meng, Y Zhao, B Han, C Zha, Y Zhang, Z Li… - Nature …, 2020 - nature.com
Activation of receptor tyrosine kinase (RTK) protein is frequently observed in malignant
progression of gliomas. In this study, the crosstalk activation of epidermal growth factor receptor (…
progression of gliomas. In this study, the crosstalk activation of epidermal growth factor receptor (…
[HTML][HTML] ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma
Rationale: Glioma is the most common primary malignant brain tumor in adults. Chemoresistance
of temozolomide (TMZ), the first-line chemotherapeutic agent, is a major issue in the …
of temozolomide (TMZ), the first-line chemotherapeutic agent, is a major issue in the …
[HTML][HTML] DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in …
X Meng, C Duan, H Pang, Q Chen, B Han, C Zha… - …, 2019 - thelancet.com
Background DNA damage repair (DDR) alterations are important events in cancer initiation,
progression, and therapeutic resistance. However, the involvement of DDR alterations in …
progression, and therapeutic resistance. However, the involvement of DDR alterations in …
[HTML][HTML] NoncoRNA: a database of experimentally supported non-coding RNAs and drug targets in cancer
L Li, P Wu, Z Wang, X Meng, C Zha, Z Li, T Qi… - Journal of Hematology & …, 2020 - Springer
NoncoRNA ( http://www.ncdtcdb.cn:8080/NoncoRNA/ ) is a manually curated database of
experimentally supported non-coding RNAs (ncRNAs) and drug target associations that aim to …
experimentally supported non-coding RNAs (ncRNAs) and drug target associations that aim to …
Platelet-derived microparticles stimulated by anti-β2GPI/β2GPI complexes induce pyroptosis of endothelial cells in antiphospholipid syndrome
L Di, C Zha, Y Liu - Platelets, 2023 - Taylor & Francis
Platelet microparticles (PMPs) are vesicles that are released by platelets into the extracellular
space and play a role in antiphospholipid antibody syndromes. PMPs have recently been …
space and play a role in antiphospholipid antibody syndromes. PMPs have recently been …
Tumor cell–derived TGFβ1 attenuates antitumor immune activity of T cells via regulation of PD-1 mRNA
…, B Geng, Q Chen, E Zhao, J Liu, C Sun, C Zha… - Cancer immunology …, 2020 - AACR
Dysfunction in T-cell antitumor activity contributes to the tumorigenesis, progression, and
poor outcome of clear cell renal cell carcinoma (ccRCC), with this dysfunction resulting from …
poor outcome of clear cell renal cell carcinoma (ccRCC), with this dysfunction resulting from …
Anti-β2GPI/β2GPI induces neutrophil extracellular traps formation to promote thrombogenesis via the TLR4/MyD88/MAPKs axis activation
C Zha, W Zhang, F Gao, J Xu, R Jia, J Cai, Y Liu - Neuropharmacology, 2018 - Elsevier
Antiphospholipid antibodies (aPLs) are a large group of heterogeneous antibodies that bind
to anionic phospholipids alone or in combination with phospholipid binding proteins. …
to anionic phospholipids alone or in combination with phospholipid binding proteins. …
[HTML][HTML] Platelets activated by the anti-β2GPI/β2GPI complex release microRNAs to inhibit migration and tube formation of human umbilical vein endothelial cells
Y Zhang, W Zhang, C Zha, Y Liu - Cellular & Molecular Biology Letters, 2018 - Springer
Background Patients with anti-β2GPI antibodies display significantly higher platelet
activation/aggregation and vascular endothelial cell damage. The mechanism underlying the …
activation/aggregation and vascular endothelial cell damage. The mechanism underlying the …