Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma

…, G Zhang, J Jiang, M Zhu, Y Tan, H Wang, B Lu… - Cancer immunology …, 2010 - Springer
B7-H3, a member of the B7-family molecules, plays an important role in adaptive immune
responses, and was shown to either promote or inhibit T-cell responses in various …

B7-H4 expression associates with cancer progression and predicts patient's survival in human esophageal squamous cell carcinoma

…, H Wu, S Zhou, Y Tan, M Tan, B Shan, B Lu… - Cancer immunology …, 2011 - Springer
A retrospective cohort study including 112 patients suffering from esophageal squamous
cell carcinoma (ESCC) was performed to investigate the expression of B7-H4 in ESCC and …

[HTML][HTML] Increasing the frequency of CIK cells adoptive immunotherapy may decrease risk of death in gastric cancer patients

…, WX Wei, LJ Chen, X Zheng, J Sun, BF Lu… - World journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To analyze the correlation between cytokine-induced killer (CIK) cells adoptive
immunotherapy and cancer-related death in gastric cancer patients. METHODS: One hundred and …

[HTML][HTML] IrrE, a Global Regulator of Extreme Radiation Resistance in Deinococcus radiodurans, Enhances Salt Tolerance in Escherichia coli and Brassica napus

J Pan, J Wang, Z Zhou, Y Yan, W Zhang, W Lu, S Ping… - PloS one, 2009 - journals.plos.org
Background Globally, about 20% of cultivated land is now affected by salinity. Salt tolerance
is a trait of importance to all crops in saline soils. Previous efforts to improve salt tolerance in …

Higher numbers of T-bet+ intratumoral lymphoid cells correlate with better survival in gastric cancer

…, J Chen, R Xia, S Zhou, C Wu, X Zhang, B Lu… - Cancer Immunology …, 2013 - Springer
In the present study, we studied the expression of T-bet, a key marker for type 1 immune
responses, within the tumor microenvironment of gastric cancer, and analyzed its association …

[HTML][HTML] Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory …

…, W Zhao, Y Liu, R Venkataramanan, B Lu… - Acta Pharmacologica …, 2017 - nature.com
To achieve synergistic therapeutic efficacy and prevent cancer relapse, chemotherapy and
immunotherapy have been combined as a new modality for tumor treatment. In this work, we …

[HTML][HTML] Mechanism of T cell regulation by microRNAs

J Liu, CP Wu, BF Lu, JT Jiang - Cancer biology & medicine, 2013 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small, non-coding single-stranded RNAs that can modulate target
gene expression at post-transcriptional level and participate in cell proliferation, …

Tumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk

…, HB Jie, N Gildener-Leapman, N Schmitt, BF Lu… - …, 2016 - Taylor & Francis
Programmed Death 1 (PD-1) and T cell Ig and mucin domain-3 protein (Tim-3) are immune
checkpoint receptors highly expressed on tumor infiltrating T lymphocytes (TIL). PD-1 inhibits …

[HTML][HTML] High expression of CD11c indicates favorable prognosis in patients with gastric cancer

…, B Xu, WW Hu, LJ Chen, CP Wu, BF Lu… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To determine the relationship between CD11c expression level and prognosis in
patients with gastric cancer (GC). METHODS: This retrospective survival study was performed …

Implementation of hybrid alignment algorithm for protein database search on the SW26010 many-core processor

H Zhang, Y Fu, LB Feng, Y Zhang, R Hua - IEEE Access, 2019 - ieeexplore.ieee.org
In biological research, biology sequence alignment algorithm aims to find similarities between
sequences. As the size of biological database increases exponentially, the complexity of …