Insulin, IGF1, and IGF2 are the most studied insulin-like peptides (ILPs). These are evolutionary
conserved factors well known as key regulators of energy metabolism and growth, with …

Stromal cells are essential components of the bone marrow (BM) microenvironment that
regulate and support the survival of different tumors, including chronic lymphocytic leukemia (…

Although many literature data are available on the role of Notch signaling in T-cell acute
lymphoblastic leukemia (ALL) biology, the importance of this molecular pathway in the …

Breast cancer is the most common cancer in women worldwide. Understanding the biology
of this malignant disease is a prerequisite for selecting an appropriate treatment. Cell cycle …

5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the
specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

Microbial-triggered inflammation protects against pathogens and yet can paradoxically
cause considerable secondary damage to host tissues that can result in tissue fibrosis and …

Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

Objective To obtain a scientific basis of the use of plant-derived preparations by many rural
people in Cameroon, for their primary health care needs in the treatment of diseases such as …

Mesenchymal stromal cells (MSCs) reside in many organs including lung, as shown by their
isolation from fetal lung tissues, bronchial stromal compartment, bronchial-alveolar lavage …