Safety and therapeutic potential of M2 macrophages in stroke treatment
…, MN Davydova, EV Menyaeva, AA Ostanin - Cell …, 2016 - journals.sagepub.com
Our objective was to evaluate the safety and clinical efficacy of autologous M2 macrophage
transplantation in nonacute stroke patients. We also evaluated whether the intrathecal …
transplantation in nonacute stroke patients. We also evaluated whether the intrathecal …
[HTML][HTML] The new general biological property of stem-like tumor cells (Part II: Surface molecules, which belongs to distinctive groups with particular functions, form a …
…, EV Levites, OS Taranov, AA Ostanin… - International Journal of …, 2022 - mdpi.com
An ability of poorly differentiated cells of different genesis, including tumor stem-like cells (TSCs),
to internalize extracellular double-stranded DNA (dsDNA) fragments was revealed in …
to internalize extracellular double-stranded DNA (dsDNA) fragments was revealed in …
[HTML][HTML] The new general biological property of stem-like tumor cells Part I. Peculiarities of the process of the double-stranded DNA fragments internalization into stem …
…, EV Levites, OS Taranov, AA Ostanin… - Frontiers in …, 2022 - frontiersin.org
Stem-like tumor cells of ascites carcinoma Krebs-2 and Epstein-Barr virus–induced B-lymphoma
were shown to possess the innate capability of binding and internalizing the TAMRA-…
were shown to possess the innate capability of binding and internalizing the TAMRA-…
Delivery and processing of exogenous double-stranded DNA in mouse CD34+ hematopoietic progenitor cells and their cell cycle changes upon combined treatment …
…, VP Nikolin, NA Popova, ER Chernykh, AA Ostanin… - Gene, 2013 - Elsevier
We previously reported that fragments of exogenous double-stranded DNA can be internalized
by mouse bone marrow cells without any transfection. Our present analysis shows that …
by mouse bone marrow cells without any transfection. Our present analysis shows that …
“Delayed death” phenomenon: a synergistic action of cyclophosphamide and exogenous DNA
…, AV Prokopenko, ER Chernykh, AA Ostanin… - Gene, 2012 - Elsevier
Morbidity and mortality in mice were observed upon administration of exogenous DNA
following their pre-treatment with a cytostatic agent cyclophosphamide. Upon intraperitoneal …
following their pre-treatment with a cytostatic agent cyclophosphamide. Upon intraperitoneal …
[HTML][HTML] The molecular aspects of functional activity of macrophage-activating factor GcMAF
…, ED Danilenko, OS Taranov, AA Ostanin… - International Journal of …, 2023 - mdpi.com
Group-specific component macrophage-activating factor (GcMAF) is the vitamin D 3 -binding
protein (DBP) deglycosylated at Thr 420 . The protein is believed to exhibit a wide range of …
protein (DBP) deglycosylated at Thr 420 . The protein is believed to exhibit a wide range of …
[HTML][HTML] A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA …
…, YR Efremov, ER Chernykh, AA Ostanin… - Genetic vaccines and …, 2010 - Springer
Background Immunization of mice with tumor homogenate after combined treatment with
cyclophosphamide (CP) and double-stranded DNA (dsDNA) preparation is effective at …
cyclophosphamide (CP) and double-stranded DNA (dsDNA) preparation is effective at …
[HTML][HTML] Combination of cyclophosphamide and double-stranded DNA demonstrates synergistic toxicity against established xenografts
…, EV Kiseleva, MV Zhukova, AA Ostanin… - Cancer Cell …, 2015 - Springer
Background Extracellular double-stranded DNA participates in various processes in an
organism. Here we report the suppressive effects of fragmented human double-stranded DNA …
organism. Here we report the suppressive effects of fragmented human double-stranded DNA …
Mesenchymal stromal cells improve early lymphocyte recovery and T cell reconstitution after autologous hematopoietic stem cell transplantation in patients with …
…, AV Gilevich, IV Kryuchkova, AA Ostanin… - Cellular …, 2015 - Elsevier
Mesenchymal stromal cells (MSCs) possess a multi-lineage potential and immunoregulatory
activities and provide a great potential in cell-based technologies. However, MSC …
activities and provide a great potential in cell-based technologies. However, MSC …
Effect of double-stranded DNA on maturation of dendritic cells in vitro
…, OY Leplina, LV Sakhno, ER Chernykh, AA Ostanin… - Cellular …, 2010 - Elsevier
A preparation of human genomic fragmented double-stranded DNA (dsDNA) was used as
maturation stimulus in cultures of human dendritic cells (DCs) generated in compliance with …
maturation stimulus in cultures of human dendritic cells (DCs) generated in compliance with …