The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Patient-derived organoids (PDO) are a new biomedical research model that can reconstruct
phenotypic and genetic characteristics of the original tissue and are useful for research on …

Malignant tumors are complex structures composed of cancer cells and tumor
microenvironmental cells. In this complex structure, cells cross-talk and interact, thus jointly …

T cells are an important component of adaptive immunity and protect the host from infectious
diseases and cancers. However, uncontrolled T cell immunity may cause autoimmune …

Plasmacytoid dendritic cells (pDCs) are a pioneer cell type that produces type I interferon
(IFN-I) and promotes antiviral immune responses. However, they are tolerogenic and, when …

The mechanism by which Y. ruckeri infection induces enteritis in Chinese sturgeon remains
unclear, and the efficacy of drug prevention and control measures is not only poor but also …

Renal cell carcinoma (RCC) is a frequent urological malignancy characterized by a high rate
of metastasis and lethality. The treatment strategy for advanced RCC has moved through …

Colorectal cancer is a common clinical malignant tumor of the digestive tract, and intestinal
flora has played an important role in the development of colorectal cancer. Bifidobacteria, as …

Osteosarcoma, a common malignant tumor in children, has emerged as a major threat to the
life and health of pediatric patients. Presently, there are certain limitations in the diagnosis …

Cancer is a widespread public health issue and has become a leading cause of death in
most countries. In recent decades, immunotherapy, particularly the use of immune …