Objective To compare the differences of mitochondrial DNA (mtDNA) copies among the
tissues of esophageal squamous cell carcinoma (ESCC), para-neoplastic tissue and normal …

Change in mitochondrial DNA (mtDNA) copy number has been reported in esophageal
squamous cell carcinoma (ESCC). However, its prognostic implication in ESCC remains …

Alterations in mitochondrial DNA (mtDNA) copy numbers in various human cancers have
been studied, but any such changes in esophageal squamous cell carcinoma (ESCC) are …

We previously reported a gradual increase of relative mitochondrial DNA (mtDNA) copy
number during the progression of esophageal squamous cell carcinoma (ESCC). Because …

Background The roles of mitochondria in energy metabolism, the generation of ROS, aging,
and the initiation of apoptosis have implicated their importance in tumorigenesis. In this …

An alteration in the mitochondrial DNA (mtDNA) copy number has been detected in
numerous human cancers. However, certain changes in the mtDNA copy number that occur …

Change of mitochondrial DNA (mtDNA) copy numbers is considered to be an important
hallmark of cancers. However, whether quantitative changes in mtDNA occur during the …

Abstract Background North central China has some of the highest rates of esophageal
squamous cell carcinoma in the world with cumulative mortality surpassing 20 …

Background Experimental data suggest that mitochondria is involved in tumorigenesis.
However, little is known about the qualitative and quantitative changes of mtDNA in …

Background and objective It has been proven that the mitochondrial DNA (mtDNA)
mutations and content change were associated with increasing risk of tumorigenesis …