Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor …
Myeloid-derived suppressor cells (MDSCs) suppress antitumor immune activities and
facilitate cancer progression. Although the concept of immunosuppressive MDSCs is well …
facilitate cancer progression. Although the concept of immunosuppressive MDSCs is well …
[HTML][HTML] Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer
…, L Ji, T Zhou, L Zhang, H Long, J Fu, Z Wen… - Nature …, 2021 - nature.com
Small cell lung cancer (SCLC) is a highly malignant tumor which is eventually refractory to
any treatment. Intratumoral heterogeneity (ITH) may contribute to treatment failure. However, …
any treatment. Intratumoral heterogeneity (ITH) may contribute to treatment failure. However, …
Establishment of peripheral blood mononuclear cell-derived humanized lung cancer mouse models for studying efficacy of PD-L1/PD-1 targeted immunotherapy
Animal models used to evaluate efficacies of immune checkpoint inhibitors are insufficient
or inaccurate. We thus examined two xenograft models used for this purpose, with the aim of …
or inaccurate. We thus examined two xenograft models used for this purpose, with the aim of …
[HTML][HTML] The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer
…, L Zhang, H Long, H Yang, X Wang, Z Wen… - … for immunotherapy of …, 2019 - Springer
High-level tissue tumor mutational burden (tTMB) or blood TMB (bTMB) are associated with
better response of immunotherapy in non-small cell lung cancer (NSCLC) patients. However…
better response of immunotherapy in non-small cell lung cancer (NSCLC) patients. However…
[HTML][HTML] CircSCAP interacts with SF3A3 to inhibit the malignance of non-small cell lung cancer by activating p53 signaling
…, H Li, R Li, X Li, Y Chen, HY Wang, Z Wen - Journal of Experimental …, 2022 - Springer
Background Circular RNA (circRNA) has been recently identified as a critical regulator during
carcinogenesis. However, the biological function and potential underlying mechanisms of …
carcinogenesis. However, the biological function and potential underlying mechanisms of …
[HTML][HTML] Intratumor heterogeneity comparison among different subtypes of non-small-cell lung cancer through multi-region tissue and matched ctDNA sequencing
…, H Pan, L Zhang, H Long, H Yang, X Wang, Z Wen… - Molecular cancer, 2019 - Springer
Understanding of intratumor heterogeneity (ITH) among different non-small cell lung cancer
(NSCLC) subtypes is necessary. Whether circulating tumor DNA (ctDNA) profile could …
(NSCLC) subtypes is necessary. Whether circulating tumor DNA (ctDNA) profile could …
[PDF][PDF] The results and prognosis of different treatment modalities for solitary metastatic lung tumor from nasopharyngeal carcinoma: a retrospective study of 105 cases
J Ma, ZS Wen, P Lin, X Wang, FY Xie - Chin J Cancer, 2010 - academia.edu
(RTOG) showed that carcinomas from the lower laryngeal and nasopharyngeal regions had
much higher prevalence of micrometastasis at initial diagnosis [3]. Thanks to the use of …
much higher prevalence of micrometastasis at initial diagnosis [3]. Thanks to the use of …
THUMPD3-AS1 is correlated with non-small cell lung cancer and regulates self-renewal through miR-543 and ONECUT2
…, X Li, H Miao, R Li, D Chen, Z Wen - OncoTargets and …, 2019 - Taylor & Francis
Background Of all malignancies, lung cancer is the leading cause of death, and non-small
cell lung cancer (NSCLC) accounts for 80–85% of all lung cancers. In this study, the long non-…
cell lung cancer (NSCLC) accounts for 80–85% of all lung cancers. In this study, the long non-…
[HTML][HTML] Analysis of ERCC1, BRCA1, RRM1 and TUBB3 as predictors of prognosis in patients with non-small cell lung cancer who received cisplatin-based adjuvant …
…, RZ Luo, YF Chen, LC Zhu, Z Wen - oncology …, 2016 - spandidos-publications.com
Although adjuvant platinum-based chemotherapy has been demonstrated to improve survival
in patients with completely resected non‑small cell lung cancer (NSCLC), individualized …
in patients with completely resected non‑small cell lung cancer (NSCLC), individualized …
[HTML][HTML] Comprehensive analysis of the autophagy-dependent ferroptosis-related gene FANCD2 in lung adenocarcinoma
…, Q Ren, H Li, M Zeng, D Chen, C Xu, Y Chen, Z Wen - BMC cancer, 2022 - Springer
Background The development of lung adenocarcinoma (LUAD) involves the interactions
between cell proliferation and death. Autophagy-dependent ferroptosis, a distinctive cell death …
between cell proliferation and death. Autophagy-dependent ferroptosis, a distinctive cell death …
