The drug camptothecin has a wide range of antitumor effects in cancers including gastric
cancer, rectal and colon cancer, liver cancer, and lung cancer. Camptothecin-based drugs …

For over a century, modern therapy has been at battle with malignancy, with no apparent
victory in sight. Cancer therapies have come a long way, but they still need to be more …

Camptothecin (CPT) is a cytotoxic alkaloid that attenuates the replication cancer cells via
blocking DNA topoisomerase 1. Despite its encouraging and wide spectrum antitumour …

Abstract Twenty-(S)-camptothecin is a strongly cytotoxic molecule with excellent antitumor
activity over a wide spectrum of human cancers. However, the direct formulation is limited by …

Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …

Camptothecin (CPT), a natural plant alkaloid, has indicated potent antitumor activities via
targeting intracellular topoisomerase I. The promise that CPT holds in therapies is restricted …

Cancer is the second highest cause of death globally, with about 70% of deaths occurring in
low-or middle-income countries, thus calling for efficient cures. Nanotechnology research …

Camptothecin (CPT), a natural DNA topoisomerase 1 inhibitor, is commonly used as a
model hydrophobic compound for anticancer drug delivery research. Nanoparticle loaded …

Camptothecin was initially discovered in 1966 and since its discovery there have been a
number of analogs developed giving us a group of molecules that is simply referred to as the …

Camptothecin is a potent anti-cancer drug which has shown appreciable anti-tumor activity
against a broad spectrum of cancers such as breast, ovarian, colon, lung and stomach. The …