Metabolic regulation of gene expression by histone lactylation

…, Z Tang, H Huang, G Zhou, C Cui, Y Weng, W Liu… - Nature, 2019 - nature.com
The Warburg effect, which originally described increased production of lactate in cancer, is
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

C Moreno-Yruela, D Zhang, W Wei, M Bæk, W Liu… - Science …, 2022 - science.org
Lysine L-lactylation [K(L-la)] is a newly discovered histone mark stimulated under conditions
of high glycolysis, such as the Warburg effect. K(L-la) is associated with functions that are …

[HTML][HTML] Effects of dietary betaine on growth performance, digestive function, carcass traits, and meat quality in indigenous yellow-feathered broilers under long-term …

W Liu, Y Yuan, C Sun, B Balasubramanian, Z Zhao… - Animals, 2019 - mdpi.com
Simple Summary Heat stress, one of the major problems in tropical and subtropical regions,
adversely affects poultry production. This study was designed to evaluate the effects of …

[HTML][HTML] Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation …

W Liu, R Li, J Yin, S Guo, Y Chen, H Fan, G Li… - Journal of …, 2019 - Springer
Background Activated microglia-mediated neuroinflammation has been regarded as an
underlying key player in the pathogenesis of subarachnoid hemorrhage (SAH)-induced early …

Arbitrary-oriented ship detection framework in optical remote-sensing images

W Liu, L Ma, H Chen - IEEE geoscience and remote sensing …, 2018 - ieeexplore.ieee.org
Ship detection is a challenging problem in complex optical remote-sensing images. In this
letter, an effective ship detection framework in remote-sensing images based on the …

Modeling and design of series voltage compensator for reduction of DC-link capacitance in grid-tie solar inverter

W Liu, K Wang, HS Chung… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
A grid-tie solar inverter with a series voltage compensator for reducing the high-voltage dc-link
capacitance is presented. The compensator obtains energy from the dc link to sustain the …

Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial

Y Shi, L Zhang, X Liu, C Zhou, S Zhang, D Wang… - The lancet …, 2013 - thelancet.com
Background Icotinib, an oral EGFR tyrosine kinase inhibitor, had shown antitumour activity
and favourable toxicity in early-phase clinical trials. We aimed to investigate whether icotinib …

A privacy-preserving trust model based on blockchain for VANETs

Z Lu, W Liu, Q Wang, G Qu, Z Liu - Ieee Access, 2018 - ieeexplore.ieee.org
The public key infrastructure-based authentication protocol provides basic security services
for the vehicular ad hoc networks (VANETs). However, trust and privacy are still open issues …

[HTML][HTML] Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

J Lim, ML Lachenmayer, S Wu, W Liu, M Kundu… - PLoS …, 2015 - journals.plos.org
Disruption of proteostasis, or protein homeostasis, is often associated with aberrant
accumulation of misfolded proteins or protein aggregates. Autophagy offers protection to cells by …

Heat stress in poultry production: Mitigation strategies to overcome the future challenges facing the global poultry industry

A Nawab, F Ibtisham, G Li, B Kieser, J Wu, W Liu… - Journal of thermal …, 2018 - Elsevier
Worldwide, the effect of climatic variations has become a great challenge in poultry production.
As global climate is changing, it alters the environmental temperatures, precipitation …