Renin-angiotensin-system, a potential pharmacological candidate, in acute respiratory distress syndrome during mechanical ventilation

…, CG Magnussen, GR Zosky, S Shu, X Wei, S Hu - Pulmonary …, 2019 - Elsevier
While effective treatments for acute respiratory distress syndrome (ARDS) are lacking,
mechanical lung ventilation can sustain adequate gas exchange in critically ill patients with …

Involvement of macrophages and spinal microglia in osteoarthritis pain

T Pan, F Pan, W Gao, S Hu, D Wang - Current Rheumatology Reports, 2021 - Springer
Purpose of Review Chronic pain in osteoarthritis (OA) is characterized by pain sensitization,
which involves both peripheral and central mechanisms. Studies suggest synovial …

Protein binding hot spots prediction from sequence only by a new ensemble learning method

SS Hu, P Chen, B Wang, J Li - Amino acids, 2017 - Springer
Hot spots are interfacial core areas of binding proteins, which have been applied as targets
in drug design. Experimental methods are costly in both time and expense to locate hot spot …

[HTML][HTML] Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain

…, Y Zhang, A Liu, L Shen, H Wei, Q Lou, S Hu… - Journal of …, 2023 - Springer
Background Long-term smoking is a risk factor for chronic pain, and chronic nicotine
exposure induces pain-like effects in rodents. The anterior cingulate cortex (ACC) has been …

Continuous serratus anterior plane block improved early pulmonary function after lung cancer surgical procedure

W Gao, X Yang, J Hu, H Gu, X Wu, S Hu… - The Annals of Thoracic …, 2022 - Elsevier
Background Serratus anterior plane block (SAPB) has been proven to be an efficient way to
control postoperative pain. This study explored whether the use of continuous SAPB in …

[HTML][HTML] Xanthohumol induces ROS through NADPH oxidase, causes cell cycle arrest and apoptosis

CM Wang, J Chen, J Zhao, SS Hu, SQ Zhang… - … Medicine and Cellular …, 2021 - hindawi.com
Reactive oxygen species (ROS) are either toxic in excess or essential for redox signalling at
the physiological level, which is closely related to the site of generation. Xanthohumol (XN) …

[HTML][HTML] Multiple scenario simulation and optimization of an urban green infrastructure network based on complex network theory: a case study in Harbin City, China

S Song, SH Wang, MX Shi, SS Hu, DW Xu - Ecological Processes, 2022 - Springer
Background Urban green infrastructure (GI) networks play a significant role in ensuring
regional ecological security; however, they are highly vulnerable to the influence of urban …

[HTML][HTML] The Optimal Adjuvant Strategy of Aidi Injection With Gemcitabine and Cisplatin in Advanced Non–small Cell Lung Cancer: A Meta-analysis of 70 Randomized …

…, XF Chen, H Jiang, J Huang, Y Jiang, SS Hu… - Frontiers in …, 2021 - frontiersin.org
… Two independent reviewers (Shan-Shan Hu and Hong Jiang) selected eligible trials
using predefined inclusion and exclusion criteria. Disputes of selections were resolved by …

The hepatorenal toxicity and tumor response of chemotherapy with or without Aidi injection in advanced lung cancer: a meta-analysis of 80 randomized controlled …

…, Y Jiang, XF Chen, CQ Wang, WH Xu, Y Liu, SS Hu… - Clinical Therapeutics, 2020 - Elsevier
Purpose Chemotherapy-induced hepatorenal toxicity often decreases tolerance for further
therapies and results in poor quality of life and prognosis for patients with lung cancer. In this …

Clinical efficacy and safety of aidi injection combination with vinorelbine and cisplatin for advanced non–small-cell lung carcinoma: A systematic review and meta …

Z Xiao, Y Jiang, CQ Wang, SS Hu, XR Huang… - Pharmacological …, 2020 - Elsevier
… According to the predefined inclusion and exclusion criteria, two investigators (Shan-Shan
Hu and Yuan Jiang) independently selected eligible studies. Any disagreements were …