User profiles for Ruihao Huang

Ruihao Huang (AI/ML Researcher and Reviewer, Ph.D.)

US Food and Drug Administration
Verified email at fda.hhs.gov
Cited by 172

[HTML][HTML] Recent advances in CAR-T cell engineering

R Huang, X Li, Y He, W Zhu, L Gao, Y Liu… - Journal of hematology & …, 2020 - Springer
Chimeric antigen receptor T (CAR-T) cell therapy is regarded as an effective solution for
relapsed or refractory tumors, particularly for hematological malignancies. Although the initially …

[HTML][HTML] Strategies to enhance CAR-T persistence

Y Liu, L An, R Huang, J Xiong, H Yang, X Wang… - Biomarker …, 2022 - Springer
Chimeric antigen receptor T (CAR-T) cell therapy has significantly improved the life expectancy
for patients with refractory or relapse B cell lymphoma. As for B cell acute lymphoblastic …

[HTML][HTML] Current status and prospects of hematopoietic stem cell transplantation in China

X Wang, R Huang, X Zhang, X Zhang - Chinese medical journal, 2022 - journals.lww.com
… How to cite this article: Wang XQ, Huang RH, Zhang XH, Zhang X. Current status and prospects
of hematopoietic stem … Xiaoqi Wang and Ruihao Huang contributed equally to this work. …

[HTML][HTML] CAR-NK cell therapy for hematological malignancies: recent updates from ASH 2022

R Huang, Q Wen, X Zhang - Journal of Hematology & Oncology, 2023 - Springer
Chimeric antigen receptor (CAR)-NK cell therapy has the advantages of a low incidence of
side effects and a low cost. However, the clinical outcomes are not satisfactory due to limited …

Recursive integral method for transmission eigenvalues

R Huang, AA Struthers, J Sun, R Zhang - Journal of Computational Physics, 2016 - Elsevier
Transmission eigenvalue problems arise from inverse scattering theory for inhomogeneous
media. These non-selfadjoint problems are numerically challenging because of a …

Long short-term memory recurrent neural network for pharmacokinetic-pharmacodynamic modeling

X Liu, C Liu, R Huang, H Zhu, Q Liu… - … journal of clinical …, 2021 - search.proquest.com
Objective: Recurrent neural network (RNN) has been demonstrated as a powerful tool for
analyzing various types of time series data. There is limited knowledge about the application of …

[HTML][HTML] Amplifying STING activation by bioinspired nanomedicine for targeted chemo-and immunotherapy of acute myeloid leukemia

X Wang, R Huang, W Wu, J Xiong, Q Wen, Y Zeng… - Acta Biomaterialia, 2023 - Elsevier
Chemotherapy resistance and the tumor immune microenvironment are dual reasons for
the poor therapeutic efficacy of treating acute myeloid leukemia (AML), causing suboptimal …

Mesenchymal Stem Cells for Prophylaxis of Chronic Graft-vs-Host Disease After Haploidentical Hematopoietic Stem Cell Transplant: An Open-Label Randomized …

R Huang, T Chen, S Wang, J Wang, Y Su, J Liu… - JAMA …, 2024 - jamanetwork.com
Importance Chronic graft-vs-host disease (GVHD) limits the long-term benefit of haploidentical
hematopoietic stem cell transplant (HSCT). This clinical trial evaluated repeated infusions …

[HTML][HTML] Recent advances in ocular graft-versus-host disease

X Cheng, R Huang, S Huang, W Fan, R Yuan… - Frontiers in …, 2023 - frontiersin.org
Ocular graft-versus-host-disease (GVHD) remains a significant clinical complication after
allogeneic hematopoietic stem cell transplantation. Impaired visual function, pain, and other …