Background The identification of novel targets for recovering sorafenib resistance is pivotal
for Hepatocellular carcinoma (HCC) patients. Mitophagy is the programmed degradation of …

Objective Glioblastoma (GBM) is the most common primary malignant brain tumor regulated
by numerous genes, with poor survival outcomes and unsatisfactory response to therapy. …

Current conventional treatment strategies for glioblastoma (GBM) have limited efficacy due
to the rapid development of resistance to temozolomide (TMZ). It is particularly urgent to …

Medulloblastoma (MB) is one of the most common childhood malignant brain tumors (WHO
grade IV), traditionally divided into WNT, SHH, Group 3, and Group 4 subgroups based on …

As a hallmark for glioblastoma (GBM), high heterogeneity causes a variety of phenotypes
and therapeutic responses among GBM patients, and it contributes to treatment failure. …

Infiltration and activation of intratumoral T lymphocytes are critical for immune checkpoint
blockade (ICB) therapy. Unfortunately, the low tumor immunogenicity and immunosuppressive …

Aims To investigate cardiac pathology in critically ill patients with coronavirus disease 2019 (COVID-19)
and identify associations between pathological changes and clinical …

Glioblastoma multiforme (GBM) is the most malignant form of glioma, and the overall survival
time of patients with GBM is usually less than 14 months. Therefore, it is urgent to find new …

Considering the importance of gene expression studies for understanding the biology of
glioma stem cells (GSCs), we aimed to identify the reliable reference genes in GSCs that were …

Triggering receptor expressed on myeloid cells 1(TREM-1) is a newly identified member of
the immunoglobulin superfamily and is extensively involved in the regulation of innate …