The effect of 5-fluorouracil (5-FU) chemotherapy for gastric cancer (GC) is limited by drug-resistance.
To conquer this drug-resistance, various treatments including combination therapy …

Background/Aims: The development of multidrug resistance (MDR), which results in disease
recurrence and metastasis, is a crucial obstacle to successful chemotherapy for patients …

Intestinal injury has long been considered to play a crucial role in the pathophysiology of
sepsis and has even been characterized as the “motor” of it. Thus, we explored the effects of …

Increasing evidence indicates that long non-coding RNAs (lncRNAs) can act as crucial
regulators of tumor progression. In the present study, UXT-AS1 was found to be significantly …

Bioinspired artificial nanochannels for molecular and ionic transport have extensive applications.
However, it is still a huge challenge to achieve an intelligent transport system with high …

Objective: Organoids have recently been used as in vitro models to screen chemotherapy
drugs in combination with hyperthermia treatment in colorectal cancer. Our research aimed to …

Nasopharyngeal carcinoma (NPC) is characterised by distinct geographical distribution and
is particularly prevalent in Asian countries. But the mechanisms related to the progression of …

Gastric cancer (GC) is one of the most common malignant tumors globally. About 20–30%
of patients with gastric cancer show peritoneal implantation metastasis at the first diagnosis. …

Background/Aims. Circular RNAs (circRNAs) are often used for tumor diagnosis and treatment
owing to their high stability, high expression abundance, and strong tissue specificity. The …

Objectives Recently developed CRISPR‐dependent cytosine base editor (CBE), converting
four codons (CAA, CAG, CGA and TGG) into stop codons without DNA double‐strand breaks …