Abstract
Brown-adipose-tissue glucose utilization rate and its insulin-sensitivity were measured in vivo in the anaesthetized rat by a 2-deoxy[1-3H]glucose technique. Glucose utilization can be increased 60-fold by insulin, to reach extremely high rates. Glucose utilization and its insulin-sensitivity are modulated in accordance with physiological or pathological conditions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adipose Tissue, Brown / drug effects
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Adipose Tissue, Brown / metabolism*
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Animals
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Blood Glucose / metabolism
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Deoxyglucose / metabolism
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Female
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Glucose / metabolism*
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Insulin / blood
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Insulin / pharmacology*
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Lactation
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Obesity / metabolism
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Pregnancy
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Rats
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Rats, Inbred Strains
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Rats, Zucker
Substances
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Blood Glucose
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Insulin
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Deoxyglucose
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Glucose