What we have learned about pancreatic cancer from mouse models

Gastroenterology. 2012 May;142(5):1079-92. doi: 10.1053/j.gastro.2012.03.002. Epub 2012 Mar 8.

Authors

Pedro A Pérez-Mancera¹, Carmen Guerra, Mariano Barbacid, David A Tuveson

Affiliation

¹ Li Ka Shing Centre, Cambridge Research Institute, and Department of Oncology, Cancer Research UK, Cambridge, England.

PMID: 22406637
DOI: 10.1053/j.gastro.2012.03.002

No abstract available

Publication types

Review

MeSH terms

Animals
Carcinoma, Pancreatic Ductal / diagnosis
Carcinoma, Pancreatic Ductal / etiology*
Carcinoma, Pancreatic Ductal / therapy
Disease Models, Animal*
Genetic Engineering
Humans
Inflammation / complications
Mice
Neoplastic Stem Cells / pathology
Pancreatic Neoplasms / diagnosis
Pancreatic Neoplasms / etiology*
Pancreatic Neoplasms / therapy
Pancreatitis / complications
Proto-Oncogene Proteins / genetics
Proto-Oncogene Proteins p21(ras)
STAT3 Transcription Factor / physiology
ras Proteins / genetics

Substances

KRAS protein, human
Proto-Oncogene Proteins
STAT3 Transcription Factor
Proto-Oncogene Proteins p21(ras)
ras Proteins