Laryngeal reinnervation by ansa cervicalis nerve implantation for unilateral vocal cord paralysis in humans

J Am Coll Surg. 2007 Jan;204(1):64-72. doi: 10.1016/j.jamcollsurg.2006.08.028.

Abstract

Background: Ansa cervicalis (AC)-recurrent laryngeal nerve anastomosis (RLN) is usually not desirable for correction of paralytic dysphonia when it is difficult to find a viable distal stump of the recurrent laryngeal nerve. Nerve implantation of the thyroarytenoid muscle with the ansa cervicalis is a simple alternative method.

Study design: Ten patients with unilateral vocal cord paralysis were prospectively designed to receive nerve implantation. A minimum period of 12 months after onset of paralysis was allowed to elapse to permit possible spontaneous reinnervation or compensation. Patients were followed long enough (at least 2 years) to determine if the procedure was successful. All patients were subjected to preoperative and postoperative voice recording, acoustic analysis, and videolaryngoscopy. Some of them underwent laryngeal electromyography.

Results: Ten patients underwent nerve implantation of the thyroarytenoid muscles by using the ansa cervicalis, and 8 of 10 (80%) had improved phonatory quality. Laryngeal electromyography showed that the procedure produced satisfactory reinnervation of the thyroarytenoid muscle.

Conclusions: Nerve implantation of the thyroarytenoid muscle by the anso cervicalis is a simple and efficient alternative to nerve transfer if dense scarring at the cricothyroid articulation and lack of a viable distal stump of the recurrent laryngeal nerve preclude the procedure of nerve transfer. But careful selection of the appropriate candidate seems to be the earliest prerequisite for a successful procedure.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Electromyography
  • Female
  • Follow-Up Studies
  • Humans
  • Laryngoscopy
  • Larynx / physiopathology
  • Male
  • Middle Aged
  • Recovery of Function
  • Recurrent Laryngeal Nerve / physiopathology
  • Recurrent Laryngeal Nerve / surgery*
  • Retrospective Studies
  • Spinal Nerves / transplantation*
  • Treatment Outcome
  • Vocal Cord Paralysis / diagnosis
  • Vocal Cord Paralysis / physiopathology
  • Vocal Cord Paralysis / surgery*
  • Voice Quality / physiology