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Acinar cell carcinoma of the pancreas

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Abstract

Acinar cell carcinoma of the pancreas is a rare tumor for which the best chemotherapy regimen has not been clearly established. Here, we report on a female patient with an unusually long survival and a remarkable response to weekly paclitaxel. To our knowledge, this is the first time that paclitaxel has been associated with an objective response in this disease. The patient recurred after initial resection and failed multiple prior chemotherapeutic regimens. She received weekly paclitaxel at 80 mg/m2 and responded after eight doses, maintaining controlled disease for a total of 4 mo. We present her case in detail and review the available literature regarding this rare type of tumor.

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Authors and Affiliations

  1. Department of Radiology, Albert Einstein Jewish Hospital, Sao Paulo, Brazil

    Renato Alonso Moron

  2. Department of Gastrointestinal Oncology, M. D. Anderson Cancer Center, Houston, Texas

    Paulo Marcelo Hoff

  3. Department of Pathology, Hospital Sirian Liban’s, Sao Paulo, Brazil

    Luiz Heraldo da Câmera Lopes

  4. Department of Oncology, Hospital Sirian Liban’s, Sao Paulo, Brazil

    Antonio Carlos Buzaid

  5. Department of Oncology, Albert Einstein Jewish Hospital, Av. Albert Einstein 627/701, 05651-901, Sao Paulo, SP, Brazil

    Rachel Pimenta Riechelmann MD

Authors
  1. Rachel Pimenta Riechelmann MD
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  2. Paulo Marcelo Hoff
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  3. Renato Alonso Moron
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  4. Luiz Heraldo da Câmera Lopes
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  5. Antonio Carlos Buzaid
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Corresponding author

Correspondence to Rachel Pimenta Riechelmann MD.

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Riechelmann, R.P., Hoff, P.M., Moron, R.A. et al. Acinar cell carcinoma of the pancreas. Int J Gastrointest Canc 34, 67–72 (2003). https://doi.org/10.1385/IJGC:34:2-3:067

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  • DOI: https://doi.org/10.1385/IJGC:34:2-3:067

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