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TOPICAL REVIEW

Photoacoustic tomography and sensing in biomedicine

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Published 1 September 2009 2009 Institute of Physics and Engineering in Medicine
, , Citation Changhui Li and Lihong V Wang 2009 Phys. Med. Biol. 54 R59 DOI 10.1088/0031-9155/54/19/R01

0031-9155/54/19/R59

Abstract

Photoacoustics has been broadly studied in biomedicine, for both human and small animal tissues. Photoacoustics uniquely combines the absorption contrast of light or radio frequency waves with ultrasound resolution. Moreover, it is non-ionizing and non-invasive, and is the fastest growing new biomedical method, with clinical applications on the way. This review provides a brief recap of recent developments in photoacoustics in biomedicine, from basic principles to applications. The emphasized areas include the new imaging modalities, hybrid detection methods, photoacoustic contrast agents and the photoacoustic Doppler effect, as well as translational research topics.

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