Cancer Cell
Volume 32, Issue 3, 11 September 2017, Pages 377-391.e9
ArticleEnhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
Under an Elsevier user license
open archive
Graphical Abstract
Keywords
melanoma
tumor microenvironment
CD8+ T cells
TILs
co-inhibitors
hypoxia
HIF-1α
hypoglycemia
fatty acid catabolism
fenofibrate
Cited by (0)
- 9
Present address: Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA
- 10
Lead Contact
© 2017 Elsevier Inc.