Table 1

Characteristics of 108 patients with LGGs

Characteristicsn (%)
Median age at initial diagnosis (LGGs)35 (19–54)
Median age at transformation (sAIDHmut/G4)40 (25–62)
Gender
 Male68 (63.0%)
 Female40 (37.0%)
Blood type
 A27 (25.0%)
 B26 (24.1%)
 AB14 (13.0%)
 O31 (28.7%)
 NA10 (9.3%)
Location 1
 Left48 (44.4%)
 Right57 (52.8%)
 Both3 (2.8%)
Location 2
 Single lobe77 (71.3%)
 Across multiple lobes31 (28.7%)
Grade
 Grade 274 (68.5%)
 Grade 322 (20.4%)
 Grade 2 or 312 (11.1%)
Histological description*
 A/AA73 (67.6%)
 O/AO4 (3.7%)
 OA/AOA26 (24.1%)
 NA5 (4.6%)
Chemotherapy at initial diagnosis (LGGs)
 Yes40 (37.0%)
 No55 (50.9%)
 NA13 (12.0%)
Chemotherapy at transformation (sAIDHmut/G4)
 Yes81 (75.0%)
 No19 (17.6%)
 NA8 (7.4%)
Radiotherapy at initial diagnosis (LGGs)
 Yes78 (72.2%)
 No24 (22.2%)
 NA6 (5.6%)
Radiotherapy at transformation (sAIDHmut/G4)
 Yes18 (16.7%)
 No90 (83.3%)
1p/19q-codeleted
 Yes15 (13.9%)
 No79 (73.1%)
 NA14 (13.0%)
MGMT promoter methylation
 Yes65 (60.2%)
 No25 (23.1%)
 NA18 (16.7%)

*A, astrocytoma; AA, anaplastic astrocytoma; O, oligodendroglioma; AO, anaplastic oligodendroglioma; OA, oligoastrocytoma; AOA, anaplastic oligoastrocytoma; NA, not applicable.