Table 1

Molecular classifications for HCC

Omics	Patient No.	HCC subtype	Meaning	Reference
Genomic	300	C1–C6	Clinical implications and association with prognosis	Fujimoto et al., 2016³³
Genomic	243	MSig 1–MSig 6	Design of clinical trials for targeted therapy	Schulze et al., 2015³²
Transcriptome	91	A, B	Prediction of HCC clinical outcome at the time of diagnosis	Lee et al., 2004²⁸
Transcriptome	123	G1–G6	Identification of patients who may benefit from targeted therapies	Boyault et al., 2007²⁹
Transcriptome	603	S1–S3	Guidance for the design of future clinical trials aimed at targeting agents to distinct patient populations	Hoshida et al., 2009³⁰
Transcriptome	231	C1–C3	Prediction of the prognosis of patients with HCC and prospective therapies	Yang et al., 2020³¹
Proteome	159	S-Mb, S-Pf, S-Me	Provision of unique therapeutic opportunities	Gao et al., 2019³⁴
Proteome	110	S-I, S-II, S-III	Provision of insight into tumor biology and opportunities for personalized targeted therapies	Jiang et al., 2019³⁵