Table 1

Preoperative and postoperative volumetry of tumors in mice

GroupAnimal numberPreoperative tumor volumetry (mm3)Postoperative tumor volumetry (mm3)Radicality of tumor resection (%)
Cyclophosphamide + DNAmix1_14.6920100*
1_23.1030100*
1_35.6222.22261
1_42.4460100*
Cyclophosphamide2_15.6620100*
2_22.8182.718
2_31.9740100*
2_463.36416.25175
Control3_13.4340100*
3_241.73616.54861
3_30.1340.239
3_55.1060100*

*Total resection. Partial resection. BBB, blood–brain barrier; CNS, central nervous system; CP, cyclophosphamide; CSC, cancer stem cell; DC, dendritic cell; dsDNA, double-stranded DNA; HR, homologous repair; ICL, interstrand cross-link; MDSC, myeloid-derived suppressor cell; MMC, mitomycin C; MOF, multiple organ failure; MTIC, monomethyl triazen imidazole carboxamide; NER, nucleotide excision repair; TM, tail moment; TMZ, temozolomide.