Treatment response
| Total | Hormone receptor positive | Hormone receptor negative | Statistics | |
|---|---|---|---|---|
| Numbers | 26 | 16 | 10 | |
| ORR (%) | 15.38 | 18.75 | 10 | |
| 95% CI | (4.36–34.87) | (4.05–45.65) | (0.25–44.50) | P = 1.00† |
| DCR (%) | 80.77 | 87.5 | 70 | |
| 95% CI | (60.65–93.45) | (61.65–98.45) | (34.75–93.33) | P = 0.34‡ |
| Numbers censoring, n (%) | 8 (30.77) | 6 (37.50) | 2 (20.00) | |
| Median PFS | 5.22 | 5.88 | 4.04 | |
| 95% CI | (2.86–6.24) | (1.94–8.87) | (1.87–6.24) | |
| HR§ | – | – | – | 0.62, χ2 = 0.9595 |
| 95% CI§ | – | – | – | (0.24–1.63), P = 0.32 |
PFS, progression-free survival; CI, confidence interval; HR, hazard ratio; ORR, objective response rate; DCR, disease control rate.†The ORR/DCR comparison between groups (positive vs. triple negative) was analyzed with Fisher’s exact test. ‡The 95% CI of the ORR/DCR was calculated with the Clopper-Pearson method. §The comparison of progression-free survival between 2 groups (hormone receptor positive vs. hormone receptor negative) was performed with a log-rank test. The HR and 95% CI (hormone receptor positive vs. hormone receptor negative) were estimated with the Cox proportional-hazards model.