Table 1

The potential functional circRNAs in breast cancer

circRNAsAssociated miRNAsFunctionReference
Upregulated
 circVAPAmiR-130a-5pOncogene46
 has_circ_0125597miR-660Oncogene105
 circACAP2miR-29a/b-3pOncogene106
 has_circ_0061825miR-326Oncogene47
 has_circ_002178miR-328-3pOncogene48
 has_circ_0069094Biomarker16
 has_circ_0079876Biomarker
 has_circ_0007255miR-335-5pOncogene/biomarker49
 has_circ_0002453miR-208a
miR-3164
Oncogene/biomarker107
 has_circ_0000519miR-703-3pBiomarker108
 has_circ_100219miR-485-3pOncogene50
 circAGFG1miR-195-5pOncogene109
 has_circ_0072309miR-492Anti-oncogene/biomarker54
 has_circ_001569miR-145Oncogene57
 has_circ_0067934miR-320Oncogene110
 circKIF4AmiR-375Oncogene/biomarker111
 circDENND4CmiR-200b/cOncogene112
 circRNACERmiR-136Oncogene/biomarker113
 has_circ_001783miR-200-3pOncogene114
 has_circ_21439miR-26b
miR-335
Biomarker115
 has_circ_0006528miR-7-5pOncogene58
 has_circ_0103552miR-1236Oncogene72
 CircUBE2D2miR-1236
miR-1287
Oncogene73
 hsa_circ_0000479miR-4753/6809Oncogene116
 hsa_circ_0001846miR-661Oncogene117
 hsa_circ_0005230miR-618Oncogene118
 hsa_circ_0005505miR-3607Oncogene59
 hsa_circ_0007294miR-148a-3p
miR-152-3p
Oncogene119
 hsa_circ_0007534miR-593Oncogene120
 hsa_circ_0008039miR-432-5pOncogene121
 hsa_circ_0052112miR-125a-5pOncogene122
 hsa_circ_0072995miR-30c-2-3pOncogene123
Downregulated
 has_circ_0017650Biomarker16
 has_circ_0017536Biomarker
 has_circ_0087378miR-1260bBiomarker124
 has_circ_0001451miR-197-3pAnti-oncogene/biomarker125
 circAHNAK1miR-421Anti-oncogene126
 circITCHmiR-214
miR-17
Anti-oncogene/biomarker127
 has_circ_11783miR-365-5pBiomarker115
 circASS1miR-4443Anti-oncogene51
 has_circ_0025202miR-182-5pAnti-oncogene87
 CircKDM4CmiR-548pAnti-oncogene85
 hsa_circ_0000911miR-449aAnti-oncogene52
 hsa_circ_0001098miR-3942Anti-oncogene53
 hsa_circ_0007874N/AAnti-oncogene128