Correlations of PD-L1 expression and clinicopathological parameters in Chinese LADC patients

Variables	TPS = 1%	TPS < 1%	P	TPS = 50%	TPS < 50%	P
Total cases = 428	70	358		21	407
Age (years)			0.553			0.919
= 60	37	203		12	228
< 60	33	155		9	179
Gender			0.040*			0.040*
Male	36	137		13	160
Female	34	221		8	247
Smoking status			0.005*			0.003*
Yes	33	107		13	127
No	37	251		8	280
TNM Stage			0.020*			0.078
I-II	50	298		14	334
III-IV	20	60		7	73
Histologic subtype			< 0.001*			< 0.001*
MIA	2	15		0	17
APA	36	208		5	239
LPA	1	51		0	52
PPA	7	50		1	56
MPA	4	19		2	21
SPA	20	5		13	12
IMA	0	10		0	10

*P< 0.05 was considered as significant.

SPA vs. other histologic subtypes.

Abbreviations: LADC, lung adenocarcinoma; TPS, tumor proportion score; MIA, minimally invasive adenocarcinoma; LPA, lepidic predominant adenocarcinoma; PPA, papillary predominant adenocarcinoma; APA, acinar predominant adenocarcinoma; MPA, micropapillary predominant adenocarcinoma; SPA, solid predominant adenocarcinoma; IMA, invasive mucinous adenocarcinoma.