2

Univariate and multivariate analysis of 710 PTMC primary sites with US features for predicting skip metastasis of lymph nodes

FeaturesCasesPatients [n (%)] χ2P Multivariate model
LNs (–)LNs ( +)Odds ratio95% CIP
Size (cm)11.4270.0008.6402.007–37.1920.004
= 0.5159157 (98.7)2 (1.3)
> 0.5, = 1551500 (90.7)51 (9.3)
Taller-than-wide5.2750.0232.5721.083–6.1080.032
< 1189182 (96.3)7 (3.7)
= 1521475 (91.1)46 (8.9)
Peripheral vascularity1.2300.2891.7510.547–5.6060.345
No678629 (92.8)49 (7.2)
Yes3228 (87.5)4 (12.5)
Location21.8430.0000.5310.378–0.7450.000
Isthmus1717 (100.0)0 (0.0)
Upper249219 (88.0)30 (12.0)
Middle168151 (90.0)17 (10.0)
Lower276270 (97.8)6 (2.2)
Echogenicity1.3910.3481.3630.388–4.7860.629
Hyper or isoechoic7471 (95.9)3 (4.1)
Hypo-echoic636586 (92.1)50 (7.9)
Calcification3.9770.0291.7220.759–3.9030.193
No190182 (95.8)8 (4.2)
Yes520475 (91.3)45 (8.7)
Margin0.2340.7890.6360.167–2.4220.507
Clear5249 (94.2)3 (5.8)
Unclear658608 (92.4)50 (7.6)
Abutment/perimeter18.4210.0007.0832.488–20.1640.000
= 0.25245241 (98.4)4 (1.6)
> 0.25465416 (89.5)49 (10.5)