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Univariate and multivariate Cox regression analysis of the overlapped DEGs of GBM

Gene nameUp/DownUnivariate analysisMultivariate analysis
HR (95%CI)P HR (95%CI)P
OSMRUP0.3121.366 (1.181, 1.581)< 0.0010.2791.321 (1.136, 1.537)< 0.001
PDIA4UP0.5111.667 (1.246, 2.231)0.001
GJB2UP0.1511.164 (1.063, 1.273)0.001
FKBP9UP0.3201.378 (1.135, 1.672)0.001
STEAP3UP0.2221.248 (1.086, 1.434)0.002
HOXC10UP0.1001.105 (1.037, 1.177)0.0020.0891.093 (1.024, 1.167)0.008
ISG20UP0.2971.346 (1.112, 1.629)0.002
SCARA3UP0.3371.401 (1.127, 1.742)0.0020.2381.268 (1.018, 1.580)0.034
ZNF540Down–0.3480.706 (0.558, 0.893)0.004
IKBIPUP0.4041.498 (1.131, 1.984)0.005
KDELC2UP0.3261.385 (1.104, 1.738)0.005
SPAG4UP0.1601.174 (1.048, 1.315)0.006
C1RLUP0.2161.241 (1.065, 1.446)0.006
SLC39A10Down–0.4940.611 (0.430, 0.868)0.006–0.4240.655 (0.445, 0.963)0.031
GNSUP0.4561.578 (1.140, 2.185)0.006
KHDRBS2Down–0.1470.863 (0.775, 0.961)0.007
SLC2A10UP0.2411.273 (1.062, 1.525)0.009
DENND2AUP0.2631.301 (1.066, 1.588)0.010

Abbreviations: ݬ regression coefficient; HR, hazard ratio; CI, confidence interval.