S3

The clinical information of GBM patients from GEO database

CharacteristicGSE4290GSE16011GSE43378GSE59612GSE83300GSE90604
Normal tissues23801707
GBM cases8115932755016
GBM_gender
Male10820442410
Female511231256
Missing8100010
GBM_age
=50NA107226719NA
<50NA5210831NA
GBM_grade
I-III000000
IV8115532755016
GBM_cases with survivalNA15532NA50NA

NA, not available.

Notes:

(1) All the GBM cases in the above GEO datasets were included in our study except for 4 of 159 GBM cases in GSE16011 without survival information.

(2) The glioma samples but not GBM samples in GSE4290 (26 astrocytoma and 50 oligodendroglioma), GSE16011 (29 astrocytoma, 8 pilocytic astrocytoma, 52 oligodendroglioma and 28 mixed glioma) and GSE43378 (5 astrocytoma and 13 anaplastic oligodendroglioma) were not included in our study.

(3) In GSE90604, the data from 7 normal brain tissues were included while the data from 2 normal astrocyte cell lines were excluded in our study.