Multivariate Cox analysis for overall survival
| Characteristics | HR | 95%CI | P |
| Gender | 0.137 | ||
| Male | 1 | ||
| Female | 1.50 | 0.88–2.56 | |
| Age (years) | 0.954 | ||
| < 10 | 1 | ||
| 10–20 | 1.07 | 0.35–3.27 | |
| 21–30 | 0.96 | 0.37–2.48 | |
| > 30 | 1.16 | 0.40–3.35 | |
| Location | 0.913 | ||
| Extremity | 1 | ||
| Pelvis | 2019.48 | 0–3.94*10181 | |
| Other | 2845.72 | 0–5.57*10181 | |
| Tumor volume (cm3) | 0.486 | ||
| < 150 | 1 | ||
| ≥ 150 | 1.21 | 0.70–2.11 | |
| Tumor margin | 0.241 | ||
| Radical | 1 | ||
| Wide | 4.88 | 0.47–5.00 | |
| Marginal | 2.27 | 0.80–6.49 | |
| Surgery | 0.006 | ||
| Limb salvage | 1 | ||
| Amputation | 2.24 | 1.16–4.33 | |
| Treatment arms | 0.016 | ||
| The control group | 1 | ||
| the rh-endostatin group | 0.37 | 0.16–0.87 |