The top 10 significant genes whose knockout induced cell death in 143B, MG63, and U2OS-MTX300 cells
| 143B | MG63 | U2OS/MTX300 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | neg|score | neg|P | neg|fdr | ID | neg|score | neg|P | neg|fdr | ID | neg|score | neg|P | neg|fdr |
| TRRAP | 1.76E-10 | 9.75E-06 | 2.48E-04 | PDGFRA | 1.82E-10 | 9.75E-06 | 8.25E-04 | TP53RK | 5.44E-08 | 9.75E-06 | 9.90E-04 |
| PKMYT1 | 6.80E-10 | 9.75E-06 | 2.48E-04 | MAPK15 | 3.14E-10 | 9.75E-06 | 8.25E-04 | PLK4 | 9.25E-08 | 9.75E-06 | 9.90E-04 |
| RIOK1 | 1.14E-09 | 9.75E-06 | 2.48E-04 | CDK6 | 1.58E-07 | 9.75E-06 | 8.25E-04 | PLK1 | 1.98E-07 | 9.75E-06 | 9.90E-04 |
| MTOR | 2.66E-09 | 9.75E-06 | 2.48E-04 | MAST1 | 2.96E-07 | 9.75E-06 | 8.25E-04 | BRD2 | 5.22E-07 | 9.75E-06 | 9.90E-04 |
| PLK1 | 4.32E-09 | 9.75E-06 | 2.48E-04 | TP53RK | 1.01E-06 | 9.75E-06 | 8.25E-04 | GAK | 3.68E-06 | 9.75E-06 | 9.90E-04 |
| CDK2 | 9.89E-09 | 9.75E-06 | 2.48E-04 | PTK2 | 1.64E-06 | 9.75E-06 | 8.25E-04 | MTOR | 1.01E-05 | 2.92E-05 | 1.65E-03 |
| VRK1 | 1.58E-08 | 9.75E-06 | 2.48E-04 | TRRAP | 2.37E-05 | 1.66E-04 | 9.41E-03 | TRRAP | 1.10E-05 | 2.92E-05 | 1.65E-03 |
| AURKB | 3.73E-08 | 9.75E-06 | 2.48E-04 | PKMYT1 | 2.53E-05 | 1.85E-04 | 9.41E-03 | PKMYT1 | 1.19E-05 | 2.92E-05 | 1.65E-03 |
| BUB1B | 7.57E-08 | 9.75E-06 | 2.48E-04 | ILK | 2.69E-05 | 1.85E-04 | 9.41E-03 | RIOK2 | 1.22E-05 | 2.92E-05 | 1.65E-03 |
| CDK1 | 1.28E-07 | 9.75E-06 | 2.48E-04 | NRBP2 | 2.92E-05 | 1.85E-04 | 9.41E-03 | MAP3K9 | 1.71E-05 | 6.82E-05 | 3.47E-03 |