Table 3

Survival comparisons of substages according to the eighth edition

StageOS (95%CI)P
IIB (T1-3N1)T1N1 vs. T2N120.9 m (95%CI: 17.5–24.3 m) vs. 15.1 m (95%CI: 14.3–15.9 m)0.011
T1N1 vs. T3N120.9 m (95%CI: 17.5–24.3 m) vs. 12.3 m (95%CI: 11.6–13.0 m)< 0.001
T2N1 vs. T3N115.1 m (95%CI: 14.3–15.9 m) vs. 12.3 m (95%CI: 11.6–13.0 m)< 0.001
III (T1-3N2)T1N2 vs. T2N214.9 m (95%CI: 13.1–16.7 m) vs. 11.9 m (95%CI: 11.2–12.6 m)0.042
T1N2 vs. T3N214.9 m (95%CI: 13.1–16.7 m) vs. 9.5 m (95%CI: 8.5–10.5 m)< 0.001
T2N2 vs. T3N211.9 m (95%CI: 11.2–12.6 m) vs. 9.5 m (95%CI: 8.5–10.5 m)< 0.001
III (T3N2, T4N1-2)T3N2 vs. T4N09.5 m (95%CI: 8.5–10.5 m) vs. 9.1 m (95%CI: 8.6–9.6 m)0.122
T3N2 vs. T4N19.5 m (95%CI: 8.5–10.5 m) vs. 5.9 m (95%CI: 5.0–6.8 m)< 0.001
T3N2 vs. T4N29.5 m (95%CI: 8.5–10.5 m) vs. 5.8 m (95%CI: 5.0–6.6 m)0.001
T4N0 vs. T4N19.1 m (95%CI: 8.6–9.6 m) vs. 5.9 m (95%CI: 5.0–6.8 m)0.02
T4N0 vs. T4N29.1 m (95%CI: 8.6–9.6 m) vs. 5.8 m (95%CI: 5.0–6.6 m)0.036
T1N1 (IIB) vs. T2N0 (IB)20.9 m (95%CI: 17.5–24.3 m) vs. 18.5 m (95%CI: 16.8–20.2 m)0.525
T2N2 (III) vs. T3N1 (IIB)11.9 m (95%CI: 11.2–12.6 m) vs. 12.3 m (95%CI: 11.6–13.0 m)0.897
T1N2 (III) vs. T2N1 (IIB)14.9 m (95%CI: 13.1–16.7 m) vs. 15.1 m (95%CI: 14.3–15.9 m)0.481
T1N2 (III) vs. T3N0 (IIA)14.9 m (95%CI: 13.1–16.7 m) vs. 15.5 m (95%CI: 14.6–16.4 m)0.210
T2N1 (IIB) vs. T3N0 (IIA)15.1 m (95%CI: 14.3–15.9 m) vs. 15.5 m (95%CI: 14.6–16.4 m)0.445