Table 2

Clinical characteristics of stage IV osteogenic sarcoma patients who did not respond to chemotherapy and were treated with apatinib

CharacteristicsValue
Gender
 Male23/34 (67.6%)
 Female11/34 (32.4%)
Age, years
 Average35.24
 Range11–73
Distribution
 ≤ 4221/34 (61.8%)
 > 4213/34 (38.2%)
ECOG score
 02/34 (5.9%)
 117/34 (50%)
 214/34 (41.2%)
 31/34 (2.9%)
Subtype (%)
 Osteosarcoma18/34 (52.9%)
 EWS/PNET7/34 (20.6%)
 Bone UPS4/34 (11.8%)
 Chondrosarcoma3/34 (8.8%)
 Chordoma2/34 (5.9%)
Metastatic site
 Lung34/34 (100%)
 Lung and others8/34 (23.5%)

ECOG, Eastern Cooperative Oncology Group; EWS/PNET, Ewing’s sarcoma/primitive neuroectodermal tumor; UPS, undifferentiated pleomorphic sarcoma.