Stability (%) of β-E in rat plasma (n = 5)
| Nominal concentration (μg/mL) | Room temperaturea | Autosamplerb | Freeze-thawc | −20 °C for 48 hours |
|---|---|---|---|---|
| LQC (0.6) | 93.7 ± 1.0 | 94.8 ± 2.8 | 96.38 ± 1.0 | 98.0 ± 3.0 |
| MQC (2) | 97.1 ± 0.9 | 99.6 ± 2.3 | 95.9 ± 0.7 | 101.0 ± 3.4 |
| HQC (10) | 95.4 ± 0.5 | 103.1 ± 2.2 | 98.99 ± 4.6 | 103.37 ± 0.3 |
LQC, low quality control; MQC, middle quality control; HQC, high quality control; aroom temperature during 4 hours; b25 °C during 24 hours in the autosampler; c3 freezing and thawing cycles.