Potential function of exosomal RNAs in radiotherapy
| Exosomal RNAs | Cancer | Potential function | Reference |
|---|---|---|---|
| AHIF | Glioblastoma | AHIF is upregulated and associated with radiation resistance | 61 |
| miR-1246 | Breast cancer | Irradiation induces an increase in miR-1246 in TDEs, thus inhibiting the proliferation of non-irradiated cells | 62 |
| miR-23a | Nasopharyngeal carcinoma | TDEs deliver miR-23a to HUVECs, thus promoting tumor angiogenesis by targeting TSGA10 | 63 |
| miR-23a | Lung cancer | Irradiated TDEs enhance the angiogenesis of HUVECs via the miR-23a/PTEN pathway | 64 |
| miR-339-5p | Esophageal cancer | Exosome-derived miR-339-5p mediates radiosensitivity by targeting Cdc25A | 15 |
AHIF, antisense transcript of hypoxia-inducible factor; TDEs, tumor-derived exosomes; HUVECs, human umbilical vein endothelial cells.