Table 2

Relationship between RECQL4 expression and the clinicopathological features of ESCC patients

Characteristics	Cases	RECQL4 staining intensity			P
Characteristics	Cases	Low, n	Medium, n	High, n	P
Gender					0.056
Male	164	64	67	33
Female	33	10	12	11
Age, years					0.062
≥ 60	122	48	48	26
< 60	75	26	31	18
Tumor size					0.074
≥ 5 cm	83	33	30	20
< 5 cm	114	41	49	24
Tumor differentiation					0.011*
Well	35	18	12	5
Moderate	119	45	48	26
Poor	43	11	19	13
Depth of invasion					0.033*
T1–T2	44	20	15	9
T3–T4	153	54	64	3
Lymph node status					0.048*
Negative	71	34	27	10
Positive	126	41	55	30
Tumor stage					0.144
I–II	80	38	24	16
III–IV	117	36	55	28